For Researchers

image - For ResearchersThe CRE in Mental Health and Substance Use establishes the largest concentration of internationally recognised comorbidity researchers worldwide. The CRE provides an opportunity for researchers currently working in diagnostic silos (addiction, depression, anxiety and psychosis) to share skills, resources and innovations in treatment and research approaches. 

Resources developed by the CRE are available for other researchers to access through this portal. There are training opportunities within the CRE for postgraduate and postdoctoral researchers. A full list of our publications is also available.  

image - 1315543092 N2 Clearing The Clouds 0

Clearing the Cloud is a portal which contains all our proven and new online prevention and treatment programs. Improve your health with effective prevention and treatment programs. You can also sign up to be part of our current treatment research trials.



The NHMRC Centre of Research Excellence (CRE) in Mental Health and Substance Use publishes a quarterly newsletter. The purpose of the newsletter is to provide regular updates on the progress of the CRE. Each newsletter will regularly feature sections outlining the latest CRE news, new projects and publications, upcoming seminars, workshops and events. In addition, there will be feature articles focusing on particular projects and members..

To subscribe to our newsletter please click here.

Download Issue 1, 2012               Download Issue 9, 2015               Download Issue 17, 2017


Download Issue 2, 2013               Download Issue 10, 2015             Download Issue 18 2018


Download Issue 3, 2013               Download Issue 11, 2015


Download Issue 4, 2013               Download Issue 12, 2016


Download Issue 5, 2014               Download Issue 13, 2016


Download Issue 6, 2014               Download Issue 14, 2016


Download Issue 8, 2014               Download Issue 15, 2016


Download Issue 7, 2014               Download Issue 16, 2017






In this issue, we highlight the pioneering work of the Centre for Research Excellence in Mental Health and Substance Use (CREMS) Treatment Stream. We open with a Q&A with the Director CREMS Treatment Stream, A/Prof Katherine Mills and reflect on the many achievements of the Treatment Stream as well as gain an insight into exciting plans for the future. The first feature article for this issue is provided by Prof Andrew Baillie and Dr Lexine Stapinski which details innovative projects designed to better understand the interaction between anxiety and alcohol use and to evaluate integrate treatment options for this comorbidity. A/Prof Katherine Mills provides a detailed look into innovations in the treatment of co-occurring post traumatic stress disorder and substance use disorders. Dr Sally Hunt then discusses the development and dissemination of innovative e-health interventions for the treatment of mental health and substance use problems. Lastly, Dr Christina Marel concludes the issue with a discussion of the of the development and dissemination of the National Comorbidity Guidelines.

image - Shade Logo

Shade is a 10 week program for reducing drinking and helping with depression. Shade uses cognitive behaviour therapy control their substance use, alcohol use and mood. Our research shows that SHADE can help you reduce your drinking and improve your mood.

For further information on the SHADE proram contact Dr Frances Kay-Lambkin

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Climate Schools provides health education courses which aim to empower students to gain knowledge about their health and wellbeing. This knowledge will assist them in making positive and informed choices. The courses, known as modules, are based on realistic cartoon scenarios about teenagers and are designed to impart education about the use of alcohol and others drugs, the responsible consumption of alcohol, and ways to reduce alcohol and drug related harms.

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Co-existing mental health and drug and alcohol problems occur frequently in primary care and clinical settings. Despite this, health professionals rarely receive training in how to detect, assess and formulate interventions for co-existing problems and few clinical guidelines exist. Published in 2007, this Handbook provides an exciting and highly useful addition to this area. Leading clinicians from the UK, the US and Australia provide practical descriptions of assessments and interventions for co-existing problems. These will enable professionals working with co-existing problems to understand best practice and ensure that people with co-existing problems receive optimal treatment. A range of overarching approaches are covered, including: working within a cognitive behavioural framework; provision of consultation-liaison services, training and supervision; individual, group and family interventions; and  working with rurally isolated populations.

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The National Drug and Alcohol Research Centre completed one of the first studies to examine the efficacy of an integrated exposure-based therapy for co-occurring substance use disorder and post traumatic stress disorder (PTSD). This study lead to the development the Concurrent Treatment of PTSD and Substance Use Disorders Using Prolonged Exposure (COPE) Program, a cognitive-behavioral psychotherapy program designed for patients who have posttraumatic stress disorder (PTSD) and a co-occurring alcohol or drug use disorder. COPE represents an integration of two evidence-based treatments: Prolonged Exposure (PE) therapy for PTSD and Relapse Prevention for substance use disorders.

COPE is an integrated treatment, meaning that both the PTSD and substance use disorder are addressed concurrently in therapy by the same clinician, and patients can experience substantial reductions in both PTSD symptoms and substance use severity. Patients use the COPE Patient Workbook while their clinician uses the Therapist Guide to deliver treatment. The Therapist Guide is designed for clinicians on the front-line in commuity-based settings, as well as academic, hospital, and private practice settings.

The Therapist Guide and Patient Workbook are now available. 

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Published in 2003, this mongraph provides a review of the evidence base and the discussion of the complex issues around comorbidity.

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Published in 2003, this treatment guide describes a four-session cognitive behavioural intervention for regular amohetamine users.